Screening the Effect of Process Parameters on the Yields of Bioactive Compounds Extraction from Zingiber officinale Using Full Factorial Design

Abstract

In this study the use of solvent extraction technique for the extraction of
bioactive compounds from Zingiber officinale (Ginger) was investigated.
The effect of three parameters namely extraction temperature, volume of
solvents and the extraction time on the extract yield was screened using
full factorial experimental design. The experimental runs which consist
of the treatment combinations of the three parameters were performed
in Soxhlet extraction apparatus to obtain various yields of the ginger oil
extract. The results revealed that the extraction temperature, volume of
solvents and the extraction time have significant individual and
interaction effect on the extract yield resulting in highest extract yield of
29.48%. Based on the pareto analysis, the individual effects of the three
parameters on the extract yield can be ranked as follows: extraction
temperature > volume of solvent > extraction time. While the interaction
effects can be ranked as extraction temperature-volume of solvent >
extraction temperature-extraction time > volume of solvent-extraction
time. The GC-MS analysis of the ginger oil extract revealed the presence
of 24 different components with various medicinal potentials.